Title:  OT Infrastructure Engineer

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About Astellas 

Astellas is a global life sciences company committed to turning innovative science into VALUE for patients. We provide transformative therapies in disease areas that include oncology, ophthalmology, urology, immunology and women's health. Through our research and development programs, we are pioneering new healthcare solutions for diseases with high unmet medical need. Learn more at Astellas.com. 

Are you driven to make a real difference in the lives of patients? 

We're seeking passionate individuals who thrive in dynamic environments, embrace new ideas, and aren't afraid to take intelligent risks. People who act with unwavering integrity and are deeply committed to making a tangible impact.

Working Environment and Location

• This position is 100% onsite in Tralee, Ireland.
• At Astellas we recognize the importance of work/life balance, and we are proud to offer a hybrid working solution allowing time to connect with colleagues at the office with the flexibility to also work from home. We believe this will optimize the most productive work environment for all employees to succeed and deliver. Hybrid work from certain locations may be permitted in accordance with Astellas’ Responsible Flexibility Guidelines.

Purpose and Scope

• Reporting directly to the Engineering Projects & Systems Lead, the Senior Systems & OT Infrastructure Engineer will operate within the Systems Engineering team, overseeing the design, implementation, and operational support of manufacturing systems infrastructure. This role is responsible for ensuring the reliable, secure, and compliant operation of IT and OT systems that underpin critical manufacturing operations. This role is positioned to bridge the gap between traditional IT infrastructure and industrial automation, ensuring modern IT standards are applied appropriately within time critical and vendor constrained manufacturing systems. 

Role and Responsibilities

• Design and support resilient, compliant OT architectures for PLC/SCADA, DCS, MES, historians, and vendor-packaged systems. 
• Manage and optimise OT infrastructure including servers, virtualisation, storage, backup, recovery, and lifecycle processes. 
• Lead technical activities across system delivery phases including design reviews, FAT, SAT, IQ, OQ, and PQ. 
• Own and support OT system interfaces, industrial communications, and integrations using OPC, file transfer, and related protocols. 
• Coordinate with Automation, IT, Quality, Cyber Security, and external vendors to deliver secure, integrated manufacturing environments. 
• Maintain high-availability manufacturing systems through troubleshooting, network configuration, patching, validation, and incident response. 

Essential Qualifications

• Degree-qualified in Engineering, Information Systems, Computer Science, or a related technical discipline, with significant senior-level experience in OT, industrial IT, or manufacturing systems within regulated industries. 
• Strong expertise in IT/OT infrastructure including server operating systems, virtualisation (VMware/Hyper-V), backup/disaster recovery, OT networks, and cybersecurity in manufacturing environments. 
• Proven experience supporting automation and manufacturing systems, including PLC/SCADA/DCS architectures, CQV activities, and full SDLC delivery. 
• Skilled in cross-functional collaboration, technical troubleshooting across infrastructure/network/application layers, and driving continuous improvement through strong communication and proactive problem-solving. 

Benefits

Careers | Astellas

Why Astellas

• Global collaboration: Become part of a connected global business of like-minded life science leaders, all dedicated to improving patients' lives worldwide.
• Real-world patient impact: Contribute to transformative therapies that reach patients around the world, knowing your work makes a difference every day.
  
• Relentless Innovation: Join a company at the forefront of scientific breakthroughs, where you'll have the opportunity to shape the future of healthcare. 
  
• A Culture of Growth: Chart your own course within a supportive environment that values your contributions, champions your development, and empowers you to pursue your passions.

Our Organisational Values and Behaviours

Skills and Capabilities

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We are an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law.

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